Powerful Properties of CBDa: An overlooked precursor to CBD
What exactly is CBDa?
How are actions of CBDa different from CBD?
1. One of the most encouraging areas is the potential of CBDa to reduce inflammation[2,3]. Inflammation is a key factor in many chronic conditions. Researchers compared the molecular structures of CBDa with NSAIDs (nonsteroidal anti-inflammatory drugs) commonly used for inflammation and found their chemical structures to be extremely similar—both are known to inhibit COX-2 receptors. Individuals looking for help with pain management may find positive results with CBDa.
2. Research shows that CBDa may be helpful for those experiencing low mood or anxiety as it binds to the body’s 5-HT1A serotonin-producing receptors, providing anxiolytic effects. In fact, scientists have shown that CBDa has 100 times the affinity for the 5-HT receptors as compared to CBD.
3. As nausea is mediated by serotonin receptors, CBDa has also been researched for its anti-nausea properties[4,6]. A number of stressors, including radiation and chemotherapy, trigger the body to release excess serotonin, causing nausea and vomiting. By helping to reduce nausea and vomiting, CBDa may be a potential alternative to traditional anti-emetic products.
4. Recent pre-clinical research shows that CBDa may also exhibit anti-convulsive potential. CBD has been clinically studied to help reduce neuron excitability, thus helping to control seizures.
Formato, et al., Cannabidiolic Acid, a Still Overlooked Bioactive Compound: An Introductory Review and Preliminary Research. Molecules. 2020; 25(11):2638.
Which should I use -- CBD or CBDa?
*These statements have not been evaluated by the Food and Drug Administration. Our products are not intended to diagnose, treat, cure or prevent any disease. This information is presented for educational purposes only and was developed to provide health professionals with an understanding of the potential applications of cannabinoids.